References and Additional Resources

Additional Resources

Drug Addiction, Genetics, and the Brain

The Brain and Neuroscience

Adolescents and Drug Abuse

Social Circumstances and Drug Abuse



Chambers, R.A., Taylor, J.R. & Potenza, M.N. (2003). Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability. American Journal of Psychiatry 160, 1041-1052. doi:10.1176/appi.ajp.160.6.1041

Crabbe, J.C. (2002). Genetic Contributions to Addiction. Annual Review of Psychology 53, 435-462. doi: 10.1146/annurev.psych.53.100901.135142

Fergusson, D.M., Horwood, L.J. & Ridder, E.M. (2005). Tests of causal linkages between cannabis use and psychotic symptoms. Addiction 100:3, 354-366. doi: 10.1111/j.1360-0443.2005.01001.x

Freund, T.F., Katona, Il, Piomelli, D. (2003). Role of endogenous cannabinoids in synaptic signaling. Physiological Reviews 83, 1017-1066. doi: 10.1152/physrev.00004.2003.

Kelley, A.E. (2004). Memory and Addiction: Shared Neural Circuitry and Molecular Mechanisms. Neuron 44:1, 161-179. doi: 10.1016/j.neuron.2004.09.016

Lovinger, D.M. (1999). The role of serotonin in alcohol's effects on the brain. Current Separations 18:1, 23-28.

Mansvelder, H.D. & McGehee, D.S. (2002). Cellular and synaptic mechanisms of nicotine addiction. Journal of Neurobiology 53:4, 606-617. doi: 10.1002/neu.10148

Morgan, D. et al (2002). Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration. Nature Neuroscience 5, 169-174. doi: 10.1038/nn798

Nestler, E.J. (2000). Genes and addiction. Nature Genetics 26, 277-281. doi: 10.1038/81570

Nestler, E.J. & Landsman, D. (2001). Learning About Addiction From the Genome. Nature 409, 834-835. doi: 10.1038/35057015

O'Brien, C.P. (1997). A range of research-based pharmacotherapies for addiction. Science 278:5335, 66-70. doi: 10.1126/science.278.5335.66

Pandey, S.C., Roy, A., Zhang, H. & Xu, T. (2004). Partial deletion of the cAMP response element-binding protein gene promotes alcohol-drinking behaviors. The Journal of Neuroscience 24:21, 5022-5030. doi: 10.1523/JNEUROSCI.5557-03.2004

Pianezza, M.L., Sellers, E.M., & Tyndale, R.F. (1998). Nicotine metabolism defect reduces smoking. Nature 393:6687, 750. doi:10.1038/31623

Rocha, B.A. et al (1998). Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature 393, 175-178. doi: 10.1038/30259

Schinka, J.A. et al (2002). A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substances. Molecular Psychiatry 7:2, 224-228. doi: 10.1038/ sj/mp/4000951

Shirley, R.L., Walter, N.A.R., Reilly, M.T., Fehr, C. & Buck, K.J. (2004). Mpdz is a quantitative trait gene for drug withdrawal seizures. Nature Neuroscience 7, 699-700. doi: 10.1038/nn1271

Tapper, A.R. et al (2004). Nicotine activation of alpha4 receptors: sufficient for reward, tolerance, and sensitization. Science 306:5698, 1029-1032. doi: 10.1126/science.1099420

Volkow, N.D. et al (2001). Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers. The American Journal of Psychiatry 158: 3, 377-382. doi: 10.1176/appi.ajp.158.3.377

Volkow, N.D. et al (2001). Higher cortical and lower subcortical metabolism in detoxified methamphetamine abusers. The American Journal of Psychiatry 158: 3, 383-389. doi:10.1176/appi.ajp.158.3.383

Yao, L., McFarland, K., Fan, P., Jiang, Z., Inoue, Y. & Diamond, I. (2005). Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior. Proceedings of the national Academy of Sciences of the United States of America 102:24, 8746-8751. doi: 10.1073/pnas.0503419102

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