References and Additional Resources

Additional Resources

Drug Addiction, Genetics, and the Brain

The Brain and Neuroscience

Adolescents and Drug Abuse

Social Circumstances and Drug Abuse

Treatment, Prevention, and Policy


Chambers, R.A., Taylor, J.R. & Potenza, M.N. (2003). Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability. American Journal of Psychiatry 160, 1041-1052. doi:10.1176/appi.ajp.160.6.1041

Crabbe, J.C. (2002). Genetic Contributions to Addiction. Annual Review of Psychology 53, 435-462. doi: 10.1146/annurev.psych.53.100901.135142

Fergusson, D.M., Horwood, L.J. & Ridder, E.M. (2005). Tests of causal linkages between cannabis use and psychotic symptoms. Addiction 100:3, 354-366. doi: 10.1111/j.1360-0443.2005.01001.x

Freund, T.F., Katona, Il, Piomelli, D. (2003). Role of endogenous cannabinoids in synaptic signaling. Physiological Reviews 83, 1017-1066. doi: 10.1152/physrev.00004.2003.

Kelley, A.E. (2004). Memory and Addiction: Shared Neural Circuitry and Molecular Mechanisms. Neuron 44:1, 161-179. doi: 10.1016/j.neuron.2004.09.016

Lovinger, D.M. (1999). The role of serotonin in alcohol's effects on the brain. Current Separations 18:1, 23-28.

Mansvelder, H.D. & McGehee, D.S. (2002). Cellular and synaptic mechanisms of nicotine addiction. Journal of Neurobiology 53:4, 606-617. doi: 10.1002/neu.10148

Morgan, D. et al (2002). Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration. Nature Neuroscience 5, 169-174. doi: 10.1038/nn798

Nestler, E.J. (2000). Genes and addiction. Nature Genetics 26, 277-281. doi: 10.1038/81570

Nestler, E.J. & Landsman, D. (2001). Learning About Addiction From the Genome. Nature 409, 834-835. doi: 10.1038/35057015

O'Brien, C.P. (1997). A range of research-based pharmacotherapies for addiction. Science 278:5335, 66-70. doi: 10.1126/science.278.5335.66

Pandey, S.C., Roy, A., Zhang, H. & Xu, T. (2004). Partial deletion of the cAMP response element-binding protein gene promotes alcohol-drinking behaviors. The Journal of Neuroscience 24:21, 5022-5030. doi: 10.1523/JNEUROSCI.5557-03.2004

Pianezza, M.L., Sellers, E.M., & Tyndale, R.F. (1998). Nicotine metabolism defect reduces smoking. Nature 393:6687, 750. doi:10.1038/31623

Rocha, B.A. et al (1998). Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature 393, 175-178. doi: 10.1038/30259

Schinka, J.A. et al (2002). A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substances. Molecular Psychiatry 7:2, 224-228. doi: 10.1038/ sj/mp/4000951

Shirley, R.L., Walter, N.A.R., Reilly, M.T., Fehr, C. & Buck, K.J. (2004). Mpdz is a quantitative trait gene for drug withdrawal seizures. Nature Neuroscience 7, 699-700. doi: 10.1038/nn1271

Tapper, A.R. et al (2004). Nicotine activation of alpha4 receptors: sufficient for reward, tolerance, and sensitization. Science 306:5698, 1029-1032. doi: 10.1126/science.1099420

Volkow, N.D. et al (2001). Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers. The American Journal of Psychiatry 158: 3, 377-382. doi: 10.1176/appi.ajp.158.3.377

Volkow, N.D. et al (2001). Higher cortical and lower subcortical metabolism in detoxified methamphetamine abusers. The American Journal of Psychiatry 158: 3, 383-389. doi:10.1176/appi.ajp.158.3.383

Yao, L., McFarland, K., Fan, P., Jiang, Z., Inoue, Y. & Diamond, I. (2005). Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior. Proceedings of the national Academy of Sciences of the United States of America 102:24, 8746-8751. doi: 10.1073/pnas.0503419102


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