The Human Microbiome
Examples Of Symbiosis

Examples Of Symbiosis

Microbes Can Alter Behavior

Toxoplasma is a parasitic protist that can infect a range of animals, including mice, rats, and people. But to reproduce sexually, it must infect a cat. In an amazing and complex relationship, the parasite enters the brain of infected rodents, where it changes the host's behavior, making it more likely to be caught and eaten by a cat!

Mice infected with toxoplasma lose their fear of cats. They are more active, and more likely to spend time exploring open spaces. In one study, male rats were actually attracted to the smell of cat urine.

Once inside the cat, the protist enters cells in the intestinal wall, reproduces sexually, and releases cysts that are carried out with the cat's feces. From there, the cysts are picked up and eaten by the next host.

Infected people behave differently too. Toxoplasma infection is correlated with mental conditions including schizophrenia, obsessive-compulsive disorder, and autism. The link between toxoplasma infection and schizophrenia is stronger than for any single gene identified to date.

Microbes May Help Drive Evolution

Different types of wolbachia bacteria infect a range of animals that include insects and roundworms. In some species, the bacteria cause sexual incompatibility. Infected parents can reproduce with each other, and so can uninfected parents. But an infected parent and uninfected parent can't reproduce together. Wolbachia infection may create the "reproductive isolation" necessary for one species to diverge into two.

Microbes Are Important For Human Health

Human breast milk contains oligosaccharides, short chains of sugar molecules that provide absolutely no nutritional benefit to babies. Why do mothers spend energy making these molecules? It's to feed microbes that are important for the baby's developing immune system.

Formula-fed babies—who presumably have fewer of these beneficial, oligosaccharide-eating, immune-boosting microbes—are more likely than breast-fed babies to suffer from allergies. Early studies suggest that when babies drink formula that is supplemented with oligosaccharides similar to those found in breast milk, they become less likely to suffer from skin allergies and eczema during the first two years of life.

To learn more about how microbes keep us healthy, visit Your Microbial Friends.


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